Thread: Bio Prime

BIO Prime by Physique Conditioning is a new testosterone booster coming to the market over the coming months. Physique Conditioning will be working with our team at Buy-Sports-Supplement over the coming weeks in the aim of attaining feedback on the product, and we will be offering product testing and the opportunity to offer a review to early adopters.


BIO PRIME has been devised to tackle two core issues:

Protein Synthesis Process

The consumption of the appropriate amount of protein is obviously key to muscular growth, but people often don’t take in to account what bodily responses determine whether all of that protein is being utilised to build muscle. The bodies protein synthesis / degradation axis can be driven by HmB, biasing it towards synthesis, thus boosting gains in fat free mass by 2-3kg in as little as 21 days, dependent on dosage. The idea here is that by including 2g of HmB per serving, users will experience more efficient gains in mass assuming their diet / training is appropriate.

Anabolic / Catabolic Hormone Balance

There are an abundance of T-Support products available today, however, high testosterone levels can be impeded by catabolic hormones, e.g. cortisol. Very few T-Support products on the market today actually address this issue, the majority target the direct stimulation of testosterone and the inhibition of estrogen. But everything is relative, it doesn’t matter if testosterone is high if cortisol is as well, as cortisol will be blunting testosterones effect. This leaves room for a product that can drive anabolic hormone levels higher by muting catabolic hormone levels, and this is exactly how BIO PRIME takes it’s effect. This therefore makes BIO PRIME perfect for stacking with T-Support products to achieve truly potent testosterone levels.

Results of using BIO PRIME

At a headline level; BIO PRIME ingredients have been scientifically shown (journal articles attached) to:

Directly facilitate protein synthesis - promoting fat free mass gains of up to 2kg in 21 days*
Drive plasma cortisol levels lower by 39%
Boost plasma testosterone levels higher by 51%

*we’ve used a linear interpolation here, assuming that 3g of HmB results in 3kg gains in fat free mass, logic follows 2g will result in 2kg gain in mass.

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Formula

The formula per 4 capsules is as follows:

HmB - 2000mg
Phosphatidylserine – 600mg
L-Carnitine L-Tartate – 800mg

BIO-PRIME can:
• DIRECTLY PROMOTE GAINS IN LEAN MASS
• SUPPORT TESTOSTERONE
• CRUSH CATABOLIC HORMONES
• IMPROVE YOUR TESTOSTERONE – CORTISOL RATIO
• AID RECOVERY
DIRECTLY PROMOTE GAINS IN LEAN MASS

BIO-PRIME contains 2g of HmB, one of the most scientifically studied bodybuilding supplements available. HmB has been shown to be
effective in quantities of 1.5g - 3g per day and clinical trials (14) have shown that it can directly enhance muscular strength and directly
support lean mass growth.
Some hard facts regarding HmB’s potency have emerged:

• Over the course of three weeks, individuals using HmB supplementation experienced increases in total strength (measured as a
function of leg press, bench and abdominal exercises) of 13% (14).
• HmB can promote fat free mass gains in the region of 2.8kg over a 21 day period, which represents a gain of 86% more mass
versus a placebo condition (14).
• Clinical trials have also shown a 15kg improvement in hang clean and a 6kg improvement in bench press when using HmB
supplementation alone.
There is no doubt in our minds that HmB is one of the most potent and proven bodybuilding supplements on the market today, it should be a
"must have" supplement for any serious athlete looking to gain lean mass.
SUPPORT TESTOSTERONE

BIO-PRIME naturally supports testosterone in two ways:
• BIO-PRIME contains 600mg of phosphatidylserine (S-PS) which negates muscular catabolism and lowers cortisol. Lower cortisol
means higher testosterone. Hence, plasma testosterone levels have been shown to be up to 51% higher post a three week course
of S-PS' versus a placebo (16).
• Clinical trials have shown that 3-weeks of supplementation with L Carnitine L Tartrate (LCLT) can lower muscle damage produced
by high-intensity weight training, which indirectly increases testosterone levels. According to investigators, less muscle damage
may result in more hormonal receptors available for binding interactions with anabolic hormones (9,18). With more hormonal
receptors available for binding interactions with anabolic hormones, muscle growth potential concurrently increases (9,18).
Therefore, LCLT may enhance testosterone uptake via less muscle damage and increased availability of androgen receptors. CRUSH CATABOLIC HORMONES

Gains in lean mass are driven by anabolic hormones and impeded by catabolic hormonal responses. Cortisol is a catabolic hormone and
therefore prevents muscular growth.
Some effects of high cortisol levels are:
• Low testosterone (2,9,11)
• Excess fat in the abdominal region (1)
• Depression (11)
• Low libido (4, 11)
Cortisol takes it’s effect by breaking down bodily tissues so nutrients can be freed up for the repair and maintenance of areas of the body that
are under stress post exercise, cortisol has also been implicated in blocking the biosynthesis of testosterone in the testes. BIO-PRIME contains
an ingredient that has been clinically shown mute this catabolic response; studies have shown that S-PS can reduce plasma cortisol levels by
39% compared to a placebo (16).
IMPROVE YOUR TESTOSTERONE – CORTISOL RATIO

Most bodybuilders will be taking some sort of T-Support, however, levels of testosterone in the body should only ever be considered in the
context of cortisol levels, and hence, your testosterone-cortisol ratio. Essentially, the lower the levels of cortisol in the body the more effective
T-Support is. This will ultimately manifest as faster growth.

A negative T / C has been reported as being indicative of an over trained state in which muscles become sore, submaximal, testosterone
levels fall and a disturbance in the anabolic / catabolic balance expresses itself, all of which may lead to decreased performance (6). By taking BIO-PRIME you will be putting your body’s testosterone levels in a whole new context, allowing for maximum impact of anabolic
hormones and efficient gains in mass.
AID RECOVERY

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It is generally accepted that creatine kinase is an accurate indicator of cell membrane damage and neurosis of muscle fibre. S-PS has been
shown, in trained individuals, to lower the perception of muscular soreness versus a placebo (3). Interestingly, S-PS has also been clinically
proven to heighten an individual’s sense of well being post exercise (6).
Selected References available.